Investigating a Waterborne Outbreak of Cryptosporidiosis; Ireland

Mahon M, Doyle S. Waterborne outbreak of cryptosporidiosis in the South East of Ireland: weighing up the evidence. Ir J Med Sci. 2017 Jan 13. doi: 10.1007/s11845-016-1552-1.

BACKGROUND: In late Spring 2012, 12 cases of cryptosporidiosis in a town in the South East of Ireland were notified to the regional Department of Public Health.

AIM: The purpose of this paper is to describe the outbreak and the investigative process which led to the conclusion that the source was a public drinking water supply.

METHODS: Outbreak and incident control teams were convened to investigate and control the outbreak.

RESULTS: Eleven cases were speciated as Cryptosporidium parvum. GP60 analysis demonstrated that 10 were C. parvum IIaA20G3R1, indicating that the cases were linked. The public water supply was the only common risk factor identified. Increased water sampling identified Cryptosporidium muris/andersoni in the treated water at one of two water treatment plants (Water Treatment Plant, WTP A) for the supply, and on the network. C. parvum was subsequently identified in raw water from WTP A.

CONCLUSIONS: The Health Service Executive (HSE) concluded that this outbreak was “probably associated with water” produced at WTP A based on (1) descriptive epidemiological evidence suggesting water-related illness and excluding other obvious explanations; and (2) water treatment failure at WTP A. WTP A was closed to facilitate an upgrade. No boil water notice was required as a supplementary supply was available. The upgrade was completed and the incident closed in 2013.

Time to Put USEPA Back on Track

“Millions of hard-working Americans rely on affordable energy to make ends meet. However, it’s no secret that the president’s so-called Clean Power Plan, the cornerstone of the Obama administration’s climate change policy, could cost up to $292 billion. The so-called Clean Power Plan would actually have no meaningful impact on our environment and only end up reducing global temperatures by three one-hundredths of a degree Celsius. This burdensome regulation would also only lower sea level rise by the thickness of three sheets of paper.” click here

Algae Removal of Pharmaceutical and Personal Care Products (PPCPs); Lake Mead

Bai X, Acharya K. Algae-mediated removal of selected pharmaceutical and personal care products (PPCPs) from Lake Mead water. The Science of the total environment. 2017 Jan 12. pii: S0048-9697(16)32890-X. doi: 10.1016/j.scitotenv.2016.12.192.

The persistence and fate of pharmaceutical and personal care products (PPCPs) in the Lake Mead ecosystem are particularly important considering the potential ecological risks and human health impacts. This study evaluated the removal of five common PPCPs (i.e., trimethoprim, sulfamethoxazole, carbamazepine, ciprofloxacin, and triclosan) from Lake Mead water mediated by the green alga Nannochloris sp. The results from the incubation studies showed that trimethoprim and carbamazepine were highly resistant to uptake in the algal cultural medium and were measured at approximately 90%-100% of the applied dose after 14days of incubation. Sulfamethoxazole was found relatively persistent, with >60% of the applied dose remaining in the water after 14days, and its removal was mainly caused by algae-mediated photolysis. However, ciprofloxacin and triclosan dissipated significantly and nearly 100% of the compounds were removed from the water after 7days of incubation under 24h of light. Ciprofloxacin and triclosan were highly susceptible to light, and their estimated half-lives were 12.7hours for ciprofloxacin and 31.2hours for triclosan. Algae-mediated sorption contributed to 11% of the removal of trimethoprim and sulfamethoxazole, 13% of the removal of carbamazepine, and 27% of the removal of triclosan from the lake water. This research showed that 1) trimethoprim, sulfamethoxazole, and carbamazepine are quite persistent in aquatic environments and may potentially affect human health via drinking water intake; 2) photolysis is the dominant pathway to remove ciprofloxacin from aquatic ecosystems, which indicates that ciprofloxacin may have lower ecological risks compared with other PPCPs; and 3) triclosan can undergo photolysis as well as algae-mediated uptake and it may potentially affect the food web because of its high toxicity to aquatic species.

Cal. Gov. Jerry Brown Waging “Holy” War Against “Climate Change”

“California’s drought conditions are actually historically normal; water shortages are created by incompetent and scheming government.” click here

 

Point of Use Filters for Waterborne Pathogen Removal

Totaro M, Valentini P, Casini B, Miccoli M, Costa AL, Baggiani A. Experimental comparison of point-of-use filters for drinking water ultrafiltration. J Hosp Infect. 2016 Dec 1. pii: S0195-6701(16)30543-6. doi: 10.1016/j.jhin.2016.11.017.

BACKGROUND: Waterborne pathogens such as Pseudomonas spp. and Legionella spp. may persist in hospital water networks despite chemical disinfection. Point-of-use filtration represents a physical control measure that can be applied in high-risk areas to contain the exposure to such pathogens. New technologies have enabled an extension of filters’ lifetimes and have made available faucet hollow-fibre filters for water ultrafiltration.

AIM: To compare point-of-use filters applied to cold water within their period of validity.

METHODS: Faucet hollow-fibre filters (filter A), shower hollow-fibre filters (filter B) and faucet membrane filters (filter C) were contaminated in two different sets of tests with standard bacterial strains (Pseudomonas aeruginosa DSM 939 and Brevundimonas diminuta ATCC 19146) and installed at points-of-use. Every day, from each faucet, 100 L of water was flushed. Before and after flushing, 250 mL of water was collected and analysed for microbiology.

FINDINGS: There was a high capacity of microbial retention from filter C; filter B released only low Brevundimonas spp. counts; filter A showed poor retention of both micro-organisms.

CONCLUSION: Hollow-fibre filters did not show good micro-organism retention. All point-of-use filters require an appropriate maintenance of structural parameters to ensure their efficiency.

Fluoride Toxicity – A Harsh Reality

Bandlapalli Pavani, Mandava Ragini, David Banji, Otilia J F Banji, N Gouri Pratusha. Fluoride Toxicity – A Harsh Reality. International Research Journal of Pharmacy, Vol 2, Iss 4, Pp 79-85 (2011).

There are many incidents of fluoride toxicity whether it is acute or chronic. Fluoride toxicity is an environmental hazard which arises from the upper layers of geological crust and is dissolved in water. Prolonged drinking of such water causes chronic fluoride toxicity. Use of fluoride containing compounds for various purposes such as dental products, metal, glass, refrigerator and chemical industries act as a source of fluoride poisoning and increase the risk of toxicity. This review reflects the deleterious effects of fluorides on various organs in the physiological system.

Fluoride Toxicity and Cognitive Impairment; China

Spittle B. Development of Fluoride Toxicity Including Cognitive Impairment with Reduced IQ: Pathophysiology, Interactions With Other Elements, and Predisposing and Protective Factors. Fluoride. Jul-Sep2016, Vol. 49 Issue 3, Part 1, p189-193.

The development of toxicity to the fluoride ion (F) may be complex and multifactorial with a number of pathophysiological path ways being possible, with the potential for interactions between toxins involving additivity, synergism, and antagonism, and with a number of other factors having predisposing and protective effects. In addition to cognitive impairment with a reduced intelligence quotient (IQ) in children developing through other mechanisms such as disturbed thyroid hormone metabolism and sonic hedgehog signalling, other pathophysiological factors such as reduced brain glucose uptake following a fluoride-induced reduction in insulin secretion may contribute. Environmental contamination with cadmium in a coal combustion fluorosis-affected rural area within China’s Three Gorges region may contribute to the dental and skeletal health problems in the population and the possibility of interactions between Cd and F affecting cognitive functioning requires further investigation. The propensity for the development of toxicity to F may involve interactions with a number of other factors as well as the levels of F exposure.