Daily Archives: November 18, 2011

Make 29% on your money in renewable energy?

Interested? Click here for more.

Martinez et al 2011: Arsenic biotransformation as a cancer promoting factor by inducing DNA damage and disruption of repair mechanisms.

V.D. Martinez, E.A. Vucic, M. Adonis, L. Gil, and W.L. Lam. Arsenic biotransformation as a cancer promoting factor by inducing DNA damage and disruption of repair mechanisms. Mol. Biol. Int. 2011; 718974. Aug 2.

Chronic exposure to arsenic in drinking water poses a major global health concern. Populations exposed to high concentrations of arsenic-contaminated drinking water suffer serious health consequences, including alarming cancer incidence and death rates. Arsenic is biotransformed through sequential addition of methyl groups, acquired from s-adenosylmethionine (SAM). Metabolism of arsenic generates a variety of genotoxic and cytotoxic species, damaging DNA directly and indirectly, through the generation of reactive oxidative species and induction of DNA adducts, strand breaks and cross links, and inhibition of the DNA repair process itself. Since SAM is the methyl group donor used by DNA methyltransferases to maintain normal epigenetic patterns in all human cells, arsenic is also postulated to affect maintenance of normal DNA methylation patterns, chromatin structure, and genomic stability. The biological processes underlying the cancer promoting factors of arsenic metabolism, related to DNA damage and repair, will be discussed here.

Press Spin: Anything goes to keep fracking story alive, back to Pavillion, Wyoming

Water monitoring¬†wells drilled in areas of known gas bearing zones can be expected to have methane and other substances detected at some point. That by itself is not news. But in this case it helps USEPA Administrator Jackson to keep the “it could be fracking let’s ban it” story line¬†alive for a worried activist audience. An act of self-preservation for the Agency. This time it is back to Pavillion, Wyoming, which gets dredged up every year or two….click here.

Hackers cyber attack US water plant

Click here for a news article about a cyber attack affecting pump control…..

Cortes et al 2011: Boron exposure assessment using drinking water and urine in the North of Chile.

S. Cortes, E. Reynega-Delgado, A.M. Sancha, and C. Ferreccio. Boron exposure assessment using drinking water and urine in the North of Chile. Science of the Total Environment. 2011 Dec 1; 410(411):96-101.

Boron is an essential trace element for plants and humans however it is still an open question what levels of boron are actually safe for humans. This study, conducted between 2006 and 2010, measured exposure levels of boron in drinking water and urine of volunteers in Arica, an area in the North of Chile with high levels of naturally occurring boron. Samples were taken of tap and bottled water (173 and 22, respectively), as well as urine from 22 volunteers, and subsequently analyzed by inductively coupled plasma spectroscopy (ICP-OES). Boron varied in public tap water from 0.22 to 11.3mgL(-1), with a median value of 2.9mgL(-1), while concentrations of boron in bottled water varied from 0.01 to 12.2mgL(-1). Neither tap nor bottled water samples had concentrations of boron within WHO recommended limits. The concentration of boron in urine varied between 0.45 and 17.4mgL(-1), with a median of 4.28mgL(-1) and was found to be correlated with tap water sampled from the homes of the volunteers (r=0.64). Authors highly recommend that in northern Chile – where levels of boron are naturally high – that the tap and bottled water supplies be monitored in order to protect public health and that regulatory standards also be established for boron in drinking water in order to limit exposure.

Click here to obtain the full paper (fee).