Daily Archives: June 20, 2012

Fluoride in drinking water and blood pressure….

Hassan Amini, Seyed Mahmood, Taghavi Shahri, Mohamad Amini, Majid Ramezani Mehrian, Yaser Mokhayer, and Masud Yunesian. Drinking Water Fluoride and Blood Pressure? An Environmental Study. Biological Trace Element Research, Volume 144, Numbers 1-3 (2011), 157-163, DOI: 10.1007/s12011-011-9054-5

The relationship between intakes of fluoride (F) from drinking water and blood pressure has not yet been reported. We examined the relationship of F in ground water resources (GWRs) of Iran with the blood pressure of Iranian population in an ecologic study. The mean F data of the GWRs (as a surrogate for F levels in drinking water) were derived from a previously conducted study. The hypertension prevalence and the mean of systolic and diastolic blood pressures (SBP & DBP) of Iranian population by different provinces and genders were also derived from the provincial report of non-communicable disease risk factor surveillance of Iran. Statistically significant positive correlations were found between the mean concentrations of F in the GWRs and the hypertension prevalence of males (r = 0.48, p = 0.007), females (r = 0.36, p = 0.048), and overall (r = 0.495, p = 0.005). Also, statistically significant positive correlations between the mean concentrations of F in the GWRs and the mean SBP of males (r = 0.431, p = 0.018), and a borderline correlation with females (r = 0.352, p = 0.057) were found. In conclusion, we found the increase of hypertension prevalence and the SBP mean with the increase of F level in the GWRs of Iranian population.

Click here for the full paper (fee).

 

 

Fluoride associated with risk of osteosarcoma….

This study must be read carefully. The abstract below says “no signigicant” association was found. But looking at the odds ratio, an association was indeed found, albeit weak. Looks like this study lends support to the assertion that fluoride exposure is a risk factor for osteosarcoma……

F.M. Kim, C. Hayes, P.L. Williams, G.M. Whitford, K.J. Joshipura, R.N. Hoover, and C.W. Douglass. An Assessment of Bone Fluoride and Osteosarcoma. Journal of Dental Research, October 2011. vol. 90, no. 10, 1171-1176.

The association between fluoride and risk for osteosarcoma is controversial. The purpose of this study was to determine if bone fluoride levels are higher in individuals with osteosarcoma. Incident cases of osteosarcoma (N = 137) and tumor controls (N = 51) were identified by orthopedic physicians, and segments of tumor-adjacent bone and iliac crest bone were analyzed for fluoride content. Logistic regression adjusted for age and sex and potential confounders of osteosarcoma was used to estimate odds ratios (OR) and 95% confidence intervals (CI). There was no significant difference in bone fluoride levels between cases and controls. The OR adjusted for age, gender, and a history of broken bones was 1.33 (95% CI: 0.56-3.15). No significant association between bone fluoride levels and osteosarcoma risk was detected in our case-control study, based on controls with other tumor diagnoses.

Click here for the full paper (fee).

 

Fluoride in drinking water and osteosarcoma incidence rates

A negative epidemiology study using an ecologic design on a potential drinking water contaminant at best is typically published with the presumption that harm should be assumed even though it was not shown definitively by the study….but usually negative studies are not published at all because they are picked apart by peer-reviewers or others because of valid reasons why the study is not reliable. However, for some reason fluoride is an exception….this negative study is a example…..supposedly it shows that water fluoridation is safe….but it shows nothing of the sort.  This study is not helpfull at all in providing any light on the fluoride in drinking water issue….

Publication of study is evidence to me of the hypocrisy of the epidemiology sciences….

Michael Levy andBernard-Simon Leclerc. Fluoride in drinking water and osteosarcoma incidence rates in the continental United States among children and adolescents. Cancer Epidemiology, Volume 36, Issue 2, April 2012, Pages e83–e88.

Introduction

It has been suggested that fluoride in drinking water may increase the risk of osteosarcoma in children and adolescents, although the evidence is inconclusive. We investigated the association between community water fluoridation (CWF) and osteosarcoma in childhood and adolescence in the continental U.S.

Methods

We used the cumulative osteosarcoma incidence rate data from the CDC Wonder database for 1999–2006, categorized by age group, sex and states. States were categorized as low (≤30%) or high (≥85%) according to the percentage of the population receiving CWF between 1992 and 2006. Confidence intervals for the incidence rates were calculated using the Gamma distribution and the incidence rates were compared between groups using Poisson regression models.

Results

We found no sex-specific statistical differences in the national incidence rates in the younger groups (5–9, 10–14), although 15–19 males were at higher risk to osteosarcoma than females in the same age group (p < 0.001). Sex and age group specific incidence rates were similar in both CWF state categories. The higher incidence rates among 15–19 year old males vs females was not associated with the state fluoridation status. We also compared sex and age specific osteosarcoma incidence rates cumulated from 1973 to 2007 from the SEER 9 Cancer Registries for single age groups from 5 to 19. There were no statistical differences between sexes for 5–14 year old children although incidence rates for single age groups for 15–19 year old males were significantly higher than for females.

Conclusion

Our ecological analysis suggests that the water fluoridation status in the continental U.S. has no influence on osteosarcoma incidence rates during childhood and adolescence.

Click here for the full paper (fee).

Press Spin: NBC Andrea Mitchell commits “Wawagate” fraud

In days past, when professional journalists would commit the error of Andrea Mitchell, they would be fired. Perhaps it is time for Andrea Mitchell to be shown out the door by NBC….click here for the full story….

Ventura (CA) Water evaluates new wastewater disinfection technology

The patented technology uses digester gas as fuel to drive a turbine that generates electricity.  Hot exhaust air from the turbine is then passed through a series of heat exchangers that increase the temperature of the wastewater to a level that disinfects the wastewater stream. Click here for press release….