Daily Archives: January 27, 2013

Rep. Henry Waxman (D-CA) and Ed Markey (D-MA) load up to fire political guns on drinking water regulation

Wilsonian progressivism has been consistently advanced in the United States as Democrat politicians use the Safe Drinking Water Act as a crow-bar and a club. This is right out of the Democrat political play book….and now we can again expect to be called baby killers, not caring about pregnant women, wanting dirty water, etc….etc….

The first congressional hearing I attended was in the late 1980s when I observed Rep. Henry Waxman and another Democrat congressman roasted USEPA Administrator William Rielly on lead. Now, at the request of House Democrats, Reps. Henry Waxman (D-CA) and Edward Markey (D-MA), the Government Accountability Office is investigating USEPA’s mandatory selection and monitoring of potential drinking-water contaminants. A process developed through stakeholder consensus, that the Democrat lawmakers hate and have pushed to strengthen in recent years. This gives them a platform to criticize the agency and anyone else (like conservatives) who may view regulating and monitoring for non-problem, no-risk substances in water as a waste of time and money.

The GAO report is expected in summer 2013, and will focus on USEPA’s third Unregulated Contaminant Monitoring List (UCMR3). Writing more regulations, issuing fines to communities, and putting water system managers in jail will not clean up drinking water. Yelling at the world in the typical Waxman/Markey/Boxer fashion won’t do the job either. We must be serious about what it takes to have sustainable water and wastewater systems…include financial sustainability, which presumes a healthy and prosperous economy, not government handouts.

Expect copius bloviation from these representatives and others when the report is released, as well as from their counterparts in the Senate…..release of this report will be the opportunity for them to sound off once again….and shut up their wimpy opposition….

Fluoride role in central nervous system toxicity…

Shuhua X, Ziyou L, Ling Y, Fei W, Sun G. A role of fluoride on free radical generation and oxidative stress in BV-2 microglia cells. Mediators Inflamm. 2012;2012:102954. doi: 10.1155/2012/102954.

The generation of ROS and lipid peroxidation has been considered to play an important role in the pathogenesis of chronic fluoride toxicity. In the present study, we observed that fluoride activated BV-2 microglia cell line by observing OX-42 expression in immunocytochemistry. Intracellular superoxide dismutase (SOD), glutathione (GSH), malondialdehyde (MDA), reactive oxygen species (ROS), superoxide anions (O(2)(∙-)), nitric oxide synthase (NOS), nitrotyrosine (NT) and nitric oxide (NO), NOS in cell medium were determined for oxidative stress assessment. Our study found that NaF of concentration from 5 to 20 mg/L can stimuli BV-2 cells to change into activated microglia displaying upregulated OX-42 expression. SOD activities significantly decreased in fluoride-treated BV-2 cells as compared with control, and MDA concentrations and contents of ROS and O(2)(∙-) increased in NaF-treated cells. Activities of NOS in cells and medium significantly increased with fluoride concentrations in a dose-dependent manner. NT concentrations also increased significantly in 10 and 50 mg/L NaF-treated cells compared with the control cells. Our present study demonstrated that toxic effects of fluoride on the central nervous system possibly partly ascribed to activiting of microglia, which enhanced oxidative stress induced by ROS and reactive nitrogen species.