Daily Archives: February 16, 2013

Fluoride is a lipid soluble neurotoxin and enzyme poison.

Michael Czajka. Impacts of Fluoridation in Context. RMIT University, Box 2476
GPO, Melbourne, Victoria, 3001, Tel: 613-9925-2122, Fax: 613-9925-3747, Email:  MC1@pobox.com

Abstract: This review article is written from a food chemistry perspective. It focuses on the  systemic effects of fluoride (rather than the effects of fluoride on the teeth) since fluoride  research concentrates largely on the teeth to the virtual exclusion of systemic effects. This is  surprising given that fluoride is a known systemic toxin. About 400 million people (~6% of  the world’s population) drink fluoridated water. The effect of fluoride on the teeth is topical  (directly on the teeth) and not systemic, so drinking fluoridated water has no benefit. Fluoride is a lipid soluble neurotoxin and enzyme poison. Fluoride accumulates in the pineal  gland (average 9000 ppm in calcium hydroxy apatite crystals) and bone. Dental fluorosis is a marker for skeletal fluorosis. At 1 ppm 32 % of US children have dental fluorosis. At 1 ppm  some sections of the population (e.g. infants) will ingest too much fluoride. Unfluoridated  and fluoridated countries have similar rates of tooth decay. Given that fluoridation of water supplies is not necessary to maintain a reduction in tooth decay and that the side effects of ingestion are undesirable, the practice is likely to come under increasing scrutiny. More studies on the systemic effects of fluoride are urgently required.

Click here for full paper (Open Source).

Korean Dental Journal article repeats flawed study design….

This is a very typical ecologic study design used to try to show the benefits of water fluoridation. 2 different populations are compared that are roughly a decade apart in age. In short, the attributions being made are not definitive, and in fact the differences observed may be due to other confounding factors. Also, actual exposure is not measured. The authors try to hedge their claims by saying the study “suggests” effectiveness, but typically this is disregarded as fluoride advocates herald such studies as proving fluoride effectiveness, which they do not.

Se-Ho Ahn, Hae-Young You, Min-Ji Kim, Dong-Hun Han, Jin-Bom Kim, Seung-Hwa Jeong. Caries preventive effect of permanent teeth using pit and fissure sealant program and community water fluoridation program. Journal of Korean Academy of Oral Health 2012.  December 36(4):289-296 http://dx.doi.org/10.11149/jkaoh.2012.36.4.289

Objectives: The aim of this study was to evaluate the caries preventive effects of oral health programs composed of pit and fissure sealant and community water fluoridation in Hapcheon-Up, Hapcheon-Gun, the Republic of Korea.

Methods: Dental surveys were conducted on 6 to 14 year old children at Hapcheon-Up, Hapcheon-Gun in 2000 and 2009, respectively. The number of the subjects was 1,957 and 1,535 children in 2000 and 2009, respectively. The percentage of samples among total population aged 6 to 14 years in 2000 and 2009 was 90.6% and 92.3%, respectively. The obtained data from these surveys were analyzed with the PASW statistical package version 18.0 (SPSS Inc., Chicago, IL, USA). The 2009 dental health data including the prevalence of dental caries and fissure sealants on children’s permanent teeth was compared to the 2000 dental health data, and assessed using chi-square test and independent-sample t-test.

Results: DMF rate of 12-year olds was 76.9% in 2000, and it significantly decreased to 42.5% in 2009. DMFT index of 12-year olds was 3.03 in 2000, and it significantly decreased to 1.07 in 2009. The prevalence rate of sealed permanent teeth among the 12-year olds was 15.4% in 2000, and it significantly increased to 97.2% in 2009. The caries reduction rate from pit and fissure sealant added by community water fluoridation program was calculated as 44.7% in 12-year olds by the difference of DMFT index between 2000 and 2009 year. Logistic regression analysis revealed that both programs were associated with an increasing likelihood of experiencing no dental caries (OR=4.00, 95% CI; 3.23-4.95).

Conclusions: These results suggest that the oral health program composed of pit and fissure sealant and community water fluoridation in Hapcheon was very effective in caries prevention. The program should be expanded to other area to prevent dental caries among children.

Click here for full paper (Open Source).

Minimum saliva fluoride concentration for remineralization examined…

《中华口腔医学会第14次全国口腔医学学术会议(2012年会)论文汇编》2012年 加入收藏 获取最新


【摘要】:正Objective:The aim of the study was to evaluate the remineralization effect on demineralized human enamel with different concentrations of fluoride solution(NaF)by confocal laser scanning microscope(CLSM)in vitro and to find the fluoride concentration on which level the fluoride solution had the remineralizaion effect on human enamel.The study also aimed to observe the fluoride concentrations in saliva at different time points after the use of fluoride toothpaste in order to investigate the remineralization duration in vivo. Methods:There were 5 groups in experiment l.The 9 human permanent teeth were dimineralized with pH4 gel for 96 hours.Each of these teeth were made into 5 enamel specimens.These 5 enamel specimens were randomly divided into 5 groups,according to the F~- level(ppm):0.01(group B),0.1(group C),l(group D),10(group E)and deionized water(group A)as control.The effect of remineralization was assessed with confocal laser scanning microscope(CLSM)by measuring three lesion parameters(area, total and average fluorescence).In experiment 2,Fluoride Ion Specific Electrode was used to measure the fluoride concentrations in non-irritating saliva of 22 healthy subjects before and after toothbrushing with fluoride toothpastes.All the data were analyzed with software SAS8.0. Results:There was significant difference between group A and C,A and D,A and E(P0.05),but no significant difference between group A and B(P0.05).The results showed that the fluoride concentration in saliva collect-ed lmin,0.5h,lh,2h and 3h after toothbrushing were significantly higher compared with the baseline,(P0.05).The average fluoride concentration on 3 hours after toothbrushing was higher than 0.1ppm. Conclusion:The minimum fluoride concentration is 0.1ppm on which level the fluoride solution has the remineralizaion effect on human enamel. The remineralization duration after the use of the fluoride toothpaste is 3 hours.

Click here for paper (fee).