Daily Archives: June 8, 2013

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Boston (MA) is about to drown due to global warming

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NOAA: The mean sea level trend is 2.63 millimeters/year with a 95% confidence interval of +/- 0.18 mm/yr based on monthly mean sea level data from 1921 to 2006 which is equivalent to a change of 0.86 feet in 100 years.

Fluorosis may be result of activated stress response

Sierant ML, Bartlett JD.Stress Response Pathways in Ameloblasts: Implications for Amelogenesis and Dental Fluorosis. Cells. 2012 Sep 1;1(3):631-645.

Human enamel development of the permanent teeth takes place during childhood and stresses encountered during this period can have lasting effects on the appearance and structural integrity of the enamel. One of the most common examples of this is the development of dental fluorosis after childhood exposure to excess fluoride, an elemental agent used to increase enamel hardness and prevent dental caries. Currently the molecular mechanism responsible for dental fluorosis remains unknown; however, recent work suggests dental fluorosis may be the result of activated stress response pathways in ameloblasts during the development of permanent teeth. Using fluorosis as an example, the role of stress response pathways during enamel maturation is discussed.