Daily Archives: April 18, 2015

Tsunami Impact on South Chennai Groundwater Quality

Rajendran A, Mansiya C. Physico-chemical analysis of ground water samples of coastal areas of south Chennai in the post-Tsunami scenario. Ecotoxicology and Environmental Safety. 2015 Apr 8. pii: S0147-6513(15)00136-0. doi: 10.1016/j.ecoenv.2015.03.037.

The study of changes in ground water quality on the east coast of chennai due to the December 26, 2004 tsunami and other subsequent disturbances is a matter of great concern. The post-Tsunami has caused considerable plant, animal, material and ecological changes in the entire stretch of chennai coastal area. Being very close to sea and frequently subjected to coastal erosion, water quality has been a concern in this coastal strip, and especially after the recent tsunami this strip seems to be more vulnerable. In the present investigation, ten ground water samples were collected from various parts of south chennai coastal area. Physico-chemical parameters such as pH, temperature, Biochemical oxygen demand (BOD), Dissolved oxygen (DO), total solids; turbidity and fecal coliform were analyzed. The overall Water quality index (WQI) values for all the samples were found to be in the range of 68.81-74.38 which reveals a fact that the quality of all the samples is only medium to good and could be used for drinking and other domestic uses only after proper treatment. The long term adverse impacts of tsunami on ground water quality of coastal areas and the relationships that exist and among various parameters are carefully analyzed. Local residents and corporation authorities have been made aware of the quality of their drinking water and the methods to conserve the water bodies.

Paper is here (fee).


Californians Increase Emergency Room Visits Under Obamacare

“According to the Los Angeles Times, Californians have actually increased their use of emergency rooms for diagnosis of medical problems rather than using ERs for actual emergencies. That problematic scenario supposedly drove statewide support for Obamacare; overburdened emergency rooms were being used en masse by those without health insurance, thanks to provisions under California law that mandate coverage via emergency room without regard to insurance.” click here

Excessive Fluoride, Aluminum Induce Cell Death, Inhibit Cholinesterase

Akinrinade ID, Memudu AE, Ogundele OM. Fluoride and aluminium disturb neuronal morphology, transport functions, cholinesterase, lysosomal and cell cycle activities. Pathophysiology. 2015 Apr 2. pii: S0928-4680(15)00020-6. doi: 10.1016/j.pathophys.2015.03.001. 

Fluoride and aluminium have been reported to cause severe alterations in the brain. However, their exact mechanisms of neurotoxic activities remain unknown. This study was designed to investigate the role of fluoride and aluminium in neuronal transport, lysosomal, cell cycle protein and acetylcholinesterase activities.

Adult Wistar rats were given low and high doses of fluoride, aluminium and a combination of both with the control group receiving distilled water for 30 days. Blood sera and brain homogenates were quantified for alkaline phosphatase (biomarker for neuronal transport) activities. Brain sections were stained with cresyl fast violet to detect neuronal cell damage. Histochemical demonstration of acetylcholinesterase (AChE) activity and the immunohistochemical detection of cell cycle protein (anti-cyclin D) and lysosomal protein (anti-cathepsin D) were done using the antigen retrieval method.

Results showed severe histomorphologic alterations, dysregulation of membrane transport activities, inhibition of AChE activities and increased expression of lysosomal and cell cycle proteins.

These findings confirm that excessive fluoride and aluminium intake induces the progression of cell death which inhibit AChE activities and trigger the release of lysosomal and cell cycle proteins.

Click here for paper (Open Access).